Organosulfur Compounds
AdipoGen 4-Methylumbelliferone
Chemical. CAS 90-33-5. Formula C10H8O3. MW 176.17. 4-Methylumbelliferone 4-MU is a selective inhibitor of hyaluronan HA by depletion of UDP-glucuronic acid, the common substrate for HA synthesis and downregulation of hyaluronan synthase 2 and 3, MMP2 and MMP9. Since hyaluronan HA is a major component of the extracellular matrix that is synthesized in excess in cancer tissues, 4-MU has been shown to have anti-cancer activity and is involved in angiogenesis, invasion and metastasis of cancer. Fluorescent pH indicator, that is highly fluorescent in alkaline solution. Exhibits a blue fluorescence at pH7. The fluorescence intensity is pH dependent and increases to a maximum at pH10 plateau above pH10. The fluorescence at pH10.3 is approximately 100 times as intense as at pH7. Spectral data lambdaex=360nm lambdaem=448nm pH > 9.
AdipoGen Josamycin
Chemical. CAS 16846-24-5. Formula C42H69NO15. MW 827.99. Synthetic. A member of the leucomycin family of macrolide antibiotics produced by Streptomyces kitasatoensis. May overcome anticancer drug resistance by inhibiting the binding of vinblastine or cyclosporin A to P-glycoprotein Pgp. An antimicrobial against a wide variety of pathogens.
AdipoGen Thapsigargin
Chemical. CAS 67526-95-8. Formula C34H50O12. Molecular Weight 650.75. Thapsigargin is a non-competitive, cell permeable inhibitor of calcium transport by SERCAs IC50 values are cell type-dependent and range from ~2-80 nM. Inhibition of SERCAs leads to an increase in intracellular calcium, which has been linked to cell activation, release of histamine from mast cells, and increased proliferation of certain types of cancer cells. Thapsigargin shows anti-inflammatory and anti-cancer effects.
TARGETMOL CHEMICALS INC OT-551 HCL 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. OT-551 HCl is an NF-(kappa)b inhibitor a disubstituted hydroxylamine with antioxidant properties can be used for the treatment of cataracts and age-related macular degeneration and geographic atrophy (GA). purity: 99%
TARGETMOL CHEMICALS INC TETRABENAZINE METABOLITE 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Tetrabenazine Metabolite ((-)-(beta)-HTBZ) a vesicles monoamine transporter 2 (VMAT2) inhibitor is an active metabolite of Tetrabenazine. Tetrabenazine Metabolite has a high affinity for VMAT2 with a Ki of 13.4 nM. Tetrabenazine Metabolite is often used to study chorea associated with Huntington's disease and other hyperactivity disorders. purity: 95%
TARGETMOL CHEMICALS INC ABEMACICLIB METABOLITE M 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg and bulk. Please contact Fisher for quotes. Abemaciclib metabolite M20 (CDK4/6-IN-4) is an active metabolite of Abemaciclib. Abemaciclib metabolite M20 is a selective CDK4/6 inhibitor and can be used for researches on the treatment of cancer. purity: 98%
TARGETMOL CHEMICALS INC BENZCYCLANE 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Benzcyclane (Benzcyclan) is an inhibitor of platelet aggregation and also a vasodilator that can be used in a variety of peripheral circulation disorders. purity: 99%
TARGETMOL CHEMICALS INC IL-17 MODULATOR 4 5MG
Also available in 1 mg 2 mg 10 mg 25 mg 50 mg 100 mg and bulk. Please contact Fisher for quotes. IL-17 modulator 4 is a prodrug of IL-17 modulator 1 which is an efficacious modulator of IL-17. purity: 98%
eMolecules Ambeed / (S)-3-((tert-Butoxycarbonyl)amino)-5-(methylthio)pentanoic acid / 1g / 525150500 / A245403 / / 1217811-51-2 / MFCD06202399 / 263.350 / C11H21NO4S
Ambeed / (S)-3-((tert-Butoxycarbonyl)amino)-5-(methylthio)pentanoic acid / 1g / 525150500 / A245403 / / 1217811-51-2 / MFCD06202399 / 263.350 / C11H21NO4S
eMolecules Ambeed / 2-(Butylthio)-5-(4455-tetramethyl-132-dioxaborolan-2-yl)pyrimidine / 100mg / 714084361 / A1545131 / / 2828444-01-3 / [null] / 294.220 / C14H23BN2O2S
Ambeed / 2-(Butylthio)-5-(4455-tetramethyl-132-dioxaborolan-2-yl)pyrimidine / 100mg / 714084361 / A1545131 / / 2828444-01-3 / [null] / 294.220 / C14H23BN2O2S
eMolecules Ambeed / N-Cbz-L-methionine / 5g / 600841308 / A478406 / / 1152-62-1 / MFCD00065124 / 283.340 / C13H17NO4S
Ambeed / N-Cbz-L-methionine / 5g / 600841308 / A478406 / / 1152-62-1 / MFCD00065124 / 283.340 / C13H17NO4S
eMolecules Ambeed / (2R3R4S5S6R)-2-(Acetoxymethyl)-6-(phenylthio)tetrahydro-2H-pyran-345-triyl triacetate / 250mg / 649783303 / A891683 / / 108032-93-5 / MFCD01862644 / 440.460 / C20H24O9S
Ambeed / (2R3R4S5S6R)-2-(Acetoxymethyl)-6-(phenylthio)tetrahydro-2H-pyran-345-triyl triacetate / 250mg / 649783303 / A891683 / / 108032-93-5 / MFCD01862644 / 440.460 / C20H24O9S
Cell Signaling Technology Mitochondrial Fusion Promoter M1 25 mg
Mitochondrial Fusion Promoter M1 25 mg
Cell Signaling Technology DL-alpha-Difluoromethylornithine Hydrochloride (DFMO) 10 mg
DL-alpha-Difluoromethylornithine Hydrochloride (DFMO) 10 mg